Publications

 

2017

publications_48

 

 

#48
 

Distinct structural mechanisms determine substrate affinity and kinase activity of Protein Kinase Cα

Lee S, Devamani T, Song HD, Sandhu M, Larsen A, Sommese R, Jain A, Vaidehi N, Sivaramakrishnan S.
J Biol Chem. 2017 Sep 29;292(39):16300-16309
 
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Publications 47

 

#47
 

ER/K Linked GPCR-G protein fusions systematically modulate second messenger response in cells

Malik RU, Dysthe M, Ritt M, Sunahara RK, Sivaramakrishnan S.
Sci Rep. 2017 Aug 10;7(1):7749 
 
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Publications 46

 

 

#46
 

Actin turnover maintains actin filament homeostasis during cytokinetic ring contraction

Chew TG, Huang J, Palani S, Sommese R, Kamnev A, Hatano T, Gu Y, Oliferenko S, Sivaramakrishnan S, Balasubramanian MK.
J Cell Biol. 2017 Sep 4;216(9):2657-2667
 
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Publications 45

 

 

#45
 

The DRY motif and the four corners of the cubic ternary complex model 

Rovati GE, Capra V, Shaw VS, Malik RU, Sivaramakrishnan S, Neubig R. 
Cell Signal. 2017 Jul;35:16-23
 
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Publications 44

 

 

#44
 

Priming GPCR signaling through the synergistic effect of two G proteins 

Gupte TM, Malik RU, Sommese RF, Ritt M, Sivaramakrishnan S. 
Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):3756-3761
 
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Publications 43

#43
 

The GCaMP-R Family of Genetically Encoded Ratiometric Calcium Indicators 

Cho JH, Swanson CJ, Chen J, Li A, Lippert LG, Boye SE, Rose K, Sivaramakrishnan S, Chuong CM, Chow RH. 
ACS Chem Biol. 2017 Apr 21;12(4):1066-1074
 
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Publications 42

 

#42
 

The role of regulatory domains in maintaining auto-inhibition in the multi-domain kinase PKCα 

Sommese RF, Ritt M, Swanson CJ, Sivaramakrishnan S. 
J Biol Chem. 2017 Feb 17;292(7):2873-2880
 
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2016

Publications 41

 

#41
 

Calcium Stimulates Self-Assembly of Protein Kinase C α In Vitro

Swanson CJ, Sommese RF, Petersen KJ, Ritt M, Karslake J, Thomas DD, Sivaramakrishnan S.
PLoS ONE, 2016, Oct 5 11(10): e0162331
 
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Publications 40

 

 

#40
 

G Protein-selective GPCR Conformations Measured Using FRET Sensors in a Live Cell Suspension Fluorometer Assay

Semack A, Malik RU, Sivaramakrishnan S.
J Vis Exp. 2016, Sep 10;(115)
 
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Publications 38

 

 

#39
 

Patterning protein complexes on DNA nanostructures using a GFP nanobody

Sommese RF, Hariadi RF, Kim K, Liu M, Tyska MJ, Sivaramakrishnan S. 
Protein Sci. 2016 Nov;25(11):2089-2094. 
 
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Publications 37

 

#38
 

Engineering Circular Gliding of Actin Filaments Along Myosin-Patterened DNA Nanotube Rings To Study Long-Term Actin-Myosin Behaviors

Hariadi RF, Appukutty AJ, Sivaramakrishnan S. 
ACS Nano. 2016 Sep 27;10(9):8281-8
 
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Publications 39

#37
 

Substrate Affinity Differentially Influences Protein Kinase C Regulation and Inhibitor Potency

Sommese RF, Sivaramakrishnan S. 
J Biol Chem. 2016 Oct; 291(42):21963-21970
 
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Publications_36

 

 

#36
 

Structural elements in the Gαs and Gαq C-termini that mediate selective GPCR signaling.

Semack A, Sandhu M, Malik RU, Vaidehi N, Sivaramakrishnan S. 
J Biol Chem. 2016 Aug 19;291(34):17929-40
 
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publications_35

 

#35
 

Correlation between Activity and Domain Complementation in Adenylyl Cyclase Demonstrated with a Novel FRET Sensor

Ritt M, Sivaramakrishnan S. 
Mol Pharmacol. 2016 Apr;89(4):407-12
 
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2015

publications_34



#34
 

Dynamic coupling and allosteric networks in the alpha subunit of heterotrimeric G proteins.

Yao XQ, Malik RU, Griggs NW, Skjaerven L, Traynor JR, Sivaramakrishnan S, Grant BJ. 
J Biol Chem. 2016 Feb 26;291(9):4742-53
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publications_33

 

 

 

#33
 

Using Protein Dimers to Maximize the Protein Hybridization Efficiency with Multisite DNA Origami Scaffolds.

Verma V, Mallik L, Hariadi RF, Sivaramakrishnan S, Skiniotis G, Joglekar AP. 
PLoS One. 2015 Sep 8;10(9):e0137125. 
 
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Publications 32

#32
 

Mechanical coordination in motor ensembles revealed using engineered artificial myosin filaments.

Hariadi RF, Sommese RF, Adhikari AS, Taylor RE, Sutton S, Spudich JA, Sivaramakrishnan S.
Nat Nanotechnol. 2015 Aug;10(8):696-700
 
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PubImages 31

 

#31

Cellular chirality arising from the self-organization of the actin cytoskeleton.

Tee YH, Shemesh T, Thiagarajan V, Hariadi RF, Anderson KL, Page C, Volkmann N, Hanein D, Sivaramakrishnan S, Kozlov MM, Bershadsky AD
Nat Cell Biol. 2015 Apr;17(4):445-57
 
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Publications 30

 

 

 

#30

The C2 domain and altered ATP-binding loop phosphorylation at Ser359 mediate the redox-dependent increase in Protein Kinase Cδ activity.

Gong J, Yao Y, Zhang P, Udayasuryan B, Komissarova EV, Chen J, Sivaramakrishnan S, Van Eyk JE, Steinberg SF
Mol Cell Biol. 2015 May;35(10):1727-40
 
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Publications 29

 

 

 

#29

Tuning myosin-driven sorting on cellular actin networks.

Hariadi RF, Sommese RF, Sivaramakrishnan S. 
Elife. 2015 Mar 4;4 
 
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2014

Publications 28

 

 

 

#28

A method for multiprotein assembly in cells reveals independent action of kinesins in complex.

Norris SR, Soppina V, Dizaji AS, Schimert KI, Sept D, Cai D, Sivaramakrishnan S, Verhey KJ
J Cell Biol. 2014 Nov 10;207(3):393-406
 
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Publications 27

 

#27

Optofluidic lasers with a single molecular layer of gain.

Chen Q, Ritt M, Sivaramakrishnan S, Sun Y, Fan X
Lab Chip. 2014 Dec 21;14(24):4590-5
 
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publications 26

 

#26

Natural Killer Cells Eradicate Galectin-1-Deficient Glioma in the Absence of Adaptive Immunity.

Baker GJ, Chockley P, Yadav VN, Doherty R, Ritt M, Sivaramakrishnan S, Castro MG, Lowenstein PR 
Cancer Res. 2014 Sep 15;74(18):5079-90
 
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publications 25

 

#25

Harnessing the unique structural properties of isolated α-helices.

Swanson CJ, Sivaramakrishnan S. 
J Biol Chem. 2014 Sep 12;289(37):25460-7
 
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publications 24

 

#24

Conserved modular domains team up to atch-open Active protein kinase Cα.

Swanson CJ, Ritt M, Wang W, Lang MJ, Narayan A, Tesmer JJ, Westfall M, Sivaramakrishnan S.
J Biol Chem. 2014 Jun 20;289(25):17812-29.
 
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Publiications 23

 

 

#23

Myosin lever arm directs collective motion on cellular actin network.

Hariadi RF, Cale M, Sivaramakrishnan S.
Proc Natl Acad Sci U S A 2014, 111(11), 4091-6.
 
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2013 

Publications 22

 

 

#22

Analyses of conformational states of the transporter associated with antigen processing (TAP) in a native cellular membrane environment.

Geng J, Sivaramakrishnan S, Raghavan M.
J Biol Chem.  2013 Dec 27;288(52):37039-47
 
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Publications 21

 

 

#21

Agonist Activated PKCβII Translocation and Modulation of Cardiac Myocyte Contractile Function.

Hwang H, Robinson D, Rogers JB, Stevenson TK, Lang SE, Sadayappan S, Day SM, Sivaramakrishnan S, Westfall MV.
Sci Rep. 2013;3:1971
 
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Publications 20

 

 

#20

Detection of G Protein-selective G Protein-coupled Receptor (GPCR) Conformations in Live Cells.

Malik RU, Ritt M, DeVree BT, Neubig RR, Sunahara RK, Sivaramakrishnan S.
J Biol Chem. 2013 Jun 14;288(24):17167-78
 
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Publications 19

 

#19

Highly sensitive fluorescent protein FRET detection using optofluidic lasers.

Chen Q, Zhang X, Sun Y, Ritt M, Sivaramakrishnan S, Fan X. 
Lab Chip.  2013 Jul 21;13(14):2679-81
 
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Publications 18

 

#18

Visualizing and manipulating focal adhesion kinase regulation in live cells.

Ritt M, Guan JL, Sivaramakrishnan S.
J Biol Chem. 2013 Mar 29;288(13):8875-86
 
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2012

Publications 17

 

 

#17

Cell-intrinsic functional effects of the α-cardiac myosin Arg-403-Gln mutation in familial hypertrophic cardiomyopathy.

Chuan P, Sivaramakrishnan S, Ashley EA, Spudich JA.
Biophys J. 2012 Jun 20;102(12):2782-90.
 
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Publications 16

 

 

#16

Dual-beam optical tweezers.

Sivaramakrishnan S, Sung J, Dunn A, Spudich JA.
Encyclopedia of Biophysics, Ed. Gordon Roberts, Springer.
 
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2011

Publications 15

 

 

 

#15

Systematic control of protein interaction using a modular ER/K α-helix linker.

Sivaramakrishnan S, Spudich JA.
Proc Natl Acad Sci U S A. 2011 Dec 20;108(51):20467-72.
 
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Publications 14

 

 

#14

Principles of unconventional myosin function and targeting.

Hartman MA, Finan D, Sivaramakrishnan S, Spudich JA.
Annu Rev Cell Dev Biol. 2011;27:133-55
 
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2010 and earlier

Publications 13

 

 

#13

Helicity of short E-R/K peptides.

Sommese RF, Sivaramakrishnan S, Baldwin RL, Spudich JA. 
Protein Sci. 2010 Oct;19(10):2001-5.
 
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Publications 12

 

 

 

#12

Single-molecule dual-beam optical trap analysis of protein structure and function.

Sung J, Sivaramakrishnan S, Dunn A, Spudich JA. 
Methods Enzymol 2010;475:321-75.
 
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Publications 11

 

 

 

#11

Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis.

S. Sivaramakrishnan, J.A. Spudich.
Nat Rev Mol Cell Biol. 2010 Feb;11(2):128-37
 
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Publications 10

 

 

#10

Combining single molecule optical trapping and small angle X-ray scattering measurements to compute the persistence length of a protein ER/K alpha-helix.

Sivaramakrishnan S, Sung J, Ali M, Doniach S, Flyvbjerg H, Spudich JA.
Biophys J. 2009 Dec 2;97(11):2993-9
 
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Publications 9

 

 

#9

Coupled myosin VI motors facilitate unidirectional movement on an F-actin network.

Sivaramakrishnan S, Spudich JA.
J Cell Biol. 2009 Oct 5;187(1):53-60
 
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Publications 8

 

#8

Insights into human beta-cardiac myosin function from single molecule and single cell studies.

Sivaramakrishnan S, Ashley E, Leinwand L, Spudich JA.
J Cardiovasc Transl Res. 2009 Dec;2(4):426-40
 
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Publications 5

 

 

#7

Shear stress induced reorganization of the keratin intermediate filament network requires PKC zeta.

Sivaramakrishnan S, Schneider JL, Sitikov A, Goldman RD, Ridge KM. 
Mol Biol Cell, 2009 Jun;20(11):2755-65.
 
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Publications 7

 

#6

Dynamic charge interactions create surprising rigidity in the ER/K alpha-helical protein motif.

Sivaramakrishnan S, Spink BJ, Sim AY, Doniach S, Spudich JA.
Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13356-61 
 
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Publications 6

 

#5

Long single alpha-helical tail domains bridge the gap between structure and function of myosin VI.

Spink BJ, Sivaramakrishnan S, Lipfert J, Doniach S, Spudich JA. 
Nat Struct Mol Biol 2008 Jun;15(6):591-7 
 
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Publications 4

 

#4

Micromechanical properties of keratin intermediate filament networks.

Sivaramakrishnan S, DeGuilio JV, Lorand L, Goldman RD, Ridge KM.
Proc Natl Acad Sci U S A. 2008 Jan 22;105(3):889-94
 
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Publications 3

 

 

#3

Computational and Experimental Study of Turbulent Flow in a 0.4-Scale Water Model of a Continuous Steel Caster.

Yuan Q, Sivaramakrishnan S, Vanka SP, Thomas BG.
Metallurgical and Materials Transactions. 2004, 35(5), 967-982(16).
 
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Publications 2

 

 

#2

Transient Fluid Flow in the Continuous Steel-slab Casting Mold.

Thomas BG, Yuan Q, Sivaramakrishnan S, Vanka SP. 
Journal of Metals - Electronic Edition, 2002, 54(1).
 
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Publications 1

 

 

#1

Comparison of four methods to evaluate fluid velocities in a continuous slab casting mold.

B.G. Thomas, Q. Yuan, S. Sivaramakrishnan, T. Shi, S.P. Vanka and M.B. Assar, ISIJ Int., 2001, 41(10), 1262-1271.
 
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