Publications

2017

#49

Conserved salt-bridge competition triggered by phosphorylation regulates the protein interactome

#48

Distinct structural mechanisms determine substrate affinity and kinase activity of Protein Kinase Cα

#47

ER/K Linked GPCR-G protein fusions systematically modulate second messenger response in cells

#46

Actin turnover maintains actin filament homeostasis during cytokinetic ring contraction

#45

The DRY motif and the four corners of the cubic ternary complex model 

#44

Priming GPCR signaling through the synergistic effect of two G proteins 

#43

The GCaMP-R Family of Genetically Encoded Ratiometric Calcium Indicators 

#42

The role of regulatory domains in maintaining auto-inhibition in the multi-domain kinase PKCα 

2016

#41

Calcium Stimulates Self-Assembly of Protein Kinase C α In Vitro

#40

G Protein-selective GPCR Conformations Measured Using FRET Sensors in a Live Cell Suspension Fluorometer Assay

#39

Patterning protein complexes on DNA nanostructures using a GFP nanobody

#38

Engineering Circular Gliding of Actin Filaments Along Myosin-Patterened DNA Nanotube Rings To Study Long-Term Actin-Myosin Behaviors

#37

Substrate Affinity Differentially Influences Protein Kinase C Regulation and Inhibitor Potency

#36

Structural elements in the Gαs and Gαq C-termini that mediate selective GPCR signaling.

2015

#34

Dynamic coupling and allosteric networks in the alpha subunit of heterotrimeric G proteins.

#33

Using Protein Dimers to Maximize the Protein Hybridization Efficiency with Multisite DNA Origami Scaffolds.

#32

Mechanical coordination in motor ensembles revealed using engineered artificial myosin filaments.

#31

Cellular chirality arising from the self-organization of the actin cytoskeleton.

#30

The C2 domain and altered ATP-binding loop phosphorylation at Ser359 mediate the redox-dependent increase in Protein Kinase Cδ activity.

#29

Tuning myosin-driven sorting on cellular actin networks.

2014

#28

A method for multiprotein assembly in cells reveals independent action of kinesins in complex.

#27

Optofluidic lasers with a single molecular layer of gain.

#26

Natural Killer Cells Eradicate Galectin-1-Deficient Glioma in the Absence of Adaptive Immunity.

#25

Harnessing the unique structural properties of isolated α-helices.

#24

Conserved modular domains team up to atch-open Active protein kinase Cα.

#23

Myosin lever arm directs collective motion on cellular actin network.

2013 

#22

Analyses of conformational states of the transporter associated with antigen processing (TAP) in a native cellular membrane environment.

#21

Agonist Activated PKCβII Translocation and Modulation of Cardiac Myocyte Contractile Function.

#20

Detection of G Protein-selective G Protein-coupled Receptor (GPCR) Conformations in Live Cells.

#19

Highly sensitive fluorescent protein FRET detection using optofluidic lasers.

#18

Visualizing and manipulating focal adhesion kinase regulation in live cells.

2012

#17

Cell-intrinsic functional effects of the α-cardiac myosin Arg-403-Gln mutation in familial hypertrophic cardiomyopathy.

#16

Dual-beam optical tweezers.

2011

#15

Systematic control of protein interaction using a modular ER/K α-helix linker.

#14

Principles of unconventional myosin function and targeting.

2010 and earlier

#13

Helicity of short E-R/K peptides.

#12

Single-molecule dual-beam optical trap analysis of protein structure and function.

#11

Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis.

#9

Coupled myosin VI motors facilitate unidirectional movement on an F-actin network.

#8

Insights into human beta-cardiac myosin function from single molecule and single cell studies.

#7

Shear stress induced reorganization of the keratin intermediate filament network requires PKC zeta.

#6

Dynamic charge interactions create surprising rigidity in the ER/K alpha-helical protein motif.

#5

Long single alpha-helical tail domains bridge the gap between structure and function of myosin VI.

#4

Micromechanical properties of keratin intermediate filament networks.

#3

Computational and Experimental Study of Turbulent Flow in a 0.4-Scale Water Model of a Continuous Steel Caster.

#2

Transient Fluid Flow in the Continuous Steel-slab Casting Mold.

#1

Comparison of four methods to evaluate fluid velocities in a continuous slab casting mold.